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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS11
All Species:
22.42
Human Site:
Y133
Identified Species:
44.85
UniProt:
Q6UWP2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6UWP2
NP_077284.2
260
28308
Y133
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
N
Chimpanzee
Pan troglodytes
XP_511425
274
29730
F147
S
I
C
T
R
E
A
F
Q
S
M
K
E
R
N
Rhesus Macaque
Macaca mulatta
XP_001111397
255
27833
Y128
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
N
Dog
Lupus familis
XP_548249
274
29660
Y147
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3U0B3
260
28256
Y133
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
N
Rat
Rattus norvegicus
Q5M875
300
33476
L156
F
W
I
I
K
A
L
L
P
S
M
L
R
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q71R50
255
27708
Y128
S
I
C
T
R
E
A
Y
Q
S
M
K
E
R
N
Frog
Xenopus laevis
NP_001088432
181
19907
R60
A
Y
Q
S
M
K
E
R
N
I
D
D
G
H
I
Zebra Danio
Brachydanio rerio
NP_001093518
258
28208
Y131
A
I
C
T
R
E
A
Y
Q
S
M
R
E
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780227
255
28419
V127
C
L
C
T
K
L
S
V
Q
Q
M
K
E
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P33207
319
33530
V197
F
L
C
T
Q
A
A
V
K
I
M
M
K
K
K
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
L131
F
D
T
N
V
T
A
L
I
N
I
T
Q
A
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.2
97.3
89
N.A.
92.6
21.6
N.A.
N.A.
78.8
54.2
73
N.A.
N.A.
N.A.
N.A.
46.9
Protein Similarity:
100
82.1
97.3
91.6
N.A.
96.1
39
N.A.
N.A.
89.2
61.9
86.1
N.A.
N.A.
N.A.
N.A.
65.7
P-Site Identity:
100
93.3
100
93.3
N.A.
100
26.6
N.A.
N.A.
100
0
80
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
N.A.
100
20
100
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
49.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
17
75
0
0
0
0
0
0
9
0
% A
% Cys:
9
0
75
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
9
9
0
0
0
% D
% Glu:
0
0
0
0
0
59
9
0
0
0
0
0
67
0
0
% E
% Phe:
25
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% H
% Ile:
0
59
9
9
0
0
0
0
9
17
9
0
0
0
9
% I
% Lys:
0
0
0
0
17
9
0
0
9
0
0
59
9
9
17
% K
% Leu:
0
17
0
0
0
9
9
17
0
0
0
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
84
9
0
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
9
0
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
9
0
0
0
67
9
0
0
9
0
0
% Q
% Arg:
0
0
0
0
59
0
0
9
0
0
0
9
9
75
0
% R
% Ser:
50
0
0
9
0
0
9
0
0
67
0
0
0
0
0
% S
% Thr:
0
0
9
75
0
9
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
0
0
9
0
0
17
0
0
0
0
0
0
9
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _